Protein Purification
MilliporeSigma™ Calbiochem™ Tankyrase1/2 Inhibitor, XAV939
The Tankyrase1/2 Inhibitor, XAV939 controls the biological activity of Tankyrase1/2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ N-Methyl-D-aspartic Acid, Hydrate
Excitatory amino acid neurotransmitter.
MilliporeSigma™ Calbiochem™ AKR1C1 Inhibitor, 5-PBSA
The AKR1C1 Inhibitor, 5-PBSA, also referenced under CAS 4906-68-7, controls the biological activity of AKR1C1.
MilliporeSigma™ Calbiochem™ Cathepsin D Substrate I
Useful as a substrate for the determination of cathepsin D activity.
MilliporeSigma™ Calbiochem™ Proteasome Substrate III, Fluorogenic
Proteasome Substrate III, Fluorogenic, is a substrate for proteasome. Also acts as a substrate for calpain, chymotrypsin, and ingensin.
MilliporeSigma™ Calbiochem™ ET-18-OCH3
A cell-permeable and reversible cytotoxic agent that shows selective cytocidal activity against neoplastic cells and virally transformed cells.
MilliporeSigma™ Calbiochem™ Protein Lysine Methyltransferase Inhibitor, UNC0321
A cell-permeable, quinazoline analog that potently and selectively inhibits PKMT G9a (IC50 = 6nM and 9nM in two biochemical assays for CLOT and ECSD, respectively, and Ki = 63 pM, which is approximately 250-fold more potent than a closely-related analog, BIX0129
MilliporeSigma™ Calbiochem™ Cyclopamine, V. californicum
Cyclopamine, V. californicum, CAS 4449-51-8, is a cell-permeable steroidal alkaloid & cholesterol mimic that specifically antagonizes Sonic Hedgehog signaling through direct interaction with Smo.
MilliporeSigma™ Calbiochem™ Casein Kinase I Inhibitor III, PF-4800567
The Casein Kinase I Inhibitor III, PF-4800567 controls the biological activity of Casein Kinase I. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ REV-ERB Agonist II, SR9009
The REV-ERB Agonist II, SR9009 controls the biological activity of REV-ERB. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Cdk1/2 Inhibitor II, NU6102
The Cdk1/2 Inhibitor II, NU6102, also referenced under CAS 444722-95-6, controls the biological activity of Cdk1/2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ InSolution™ PERK Inhibitor I, GSK2606414
A cell-permeable pyrrolopyrimidinamine compound that acts as a highly potent inhibitor against EIF2AK3/PERK-catalyzed EIF2α Ser51 phosphorylation in kinase assays (IC50 = 0
MilliporeSigma™ Calbiochem™ ATR Inhibitor IV
A cell-permeable phenylpyrazine derivative that acts as a potent, ATP-competitive ( Ki 13nM; IC50/[ATP] = 70 nM/50μM and 128 nM/100μM), ATR-selective inhibitor with much reduced or little potency against 4 related PIKKs
MilliporeSigma™ Calbiochem™ Necrosis Inhibitor, IM-54
The Necrosis Inhibitor, IM-54, also referenced under CAS 861891-50-1, selectively blocks oxidative stress-induced necrotic cell death. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ P-Glycoprotein Inhibitor, C-4
The P-Glycoprotein Inhibitor, C-4 controls the biological activity of P-Glycoprotein. This small molecule/inhibitor is primarily used for Cancer applications.